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Therapeutic Class: Aminosalicylates

Active Ingredients: This medicine includes Mesalazine

Related Medications: Asacol HD, Delzicol, Pentasa, and Lialda

Health condition: Ulcerative colitis, Crohn's Disease

Asacol Coupon

Asacol or Generic Mesalamine Uses, Dosage & Side effects

Each Asacol 800 mg delayed-release tablet contains 400 mg of aminosalicylate Mesalamine. An acrylic-based resin Eudragit S dissolves at pH 7 and above to release the active ingredient in ileum for mollifying colon inflammation.

The drug is prescribed orally as a remission for Crohn’s disease, n enema and a rectal suppository for various bowel conditions. Varied formulations are sold under the different brand and generic names worldwide.

Why is Asacol (Mesalamine) Prescribed?

The anti-inflammatory drug treats inflammation, stomach pain, rectal bleeding, diarrhea and other such symptoms of ulcerative colitis (colon ulcer). It reduces swelling in the colon—a common symptom of most bowel diseases.

Other Uses: This medication may also be used to treat Crohn's disease.

How to use Asacol

The drug is consumed orally, usually three times a day, with food or without food or as prescribed by the doctor. Users should swallow it whole (don’t chew or crush it to prevent oral digestion in the mouth). It keeps the medicine from releasing its active ingredient anywhere else other than the colon.

Take it at the same time every day (to get maximum benefits from it) with a glass of water, at least one hour before or 2 hours after a meal.

The average dosage is based on the user’s weight, medical condition and response to the disease treatment. Do not interchange brands before consulting your doctors, as different brands sell tablets having different dosages.

Don’t consume a ruptured or broken medicine. Asacol is sold as an enteric-coated tablet to protect the special coating of the stomach. Talk to your physician if you find traces of undissolved medicine in your stool.

What if I Miss a Dose or Overdose?

Skip the missed dose if you are close to taking the next dose. If there is time, take the missed dose as soon as you remember. Accordingly, adjust the hours between two simultaneous doses. Do not take two doses in a short interval of time. If you happen to overdose, contact 1-800-222-1222 (Poison Helpline) or 911 for immediate medical attention.

Asacol Side Effects

Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), dark urine, persistent nausea/vomiting, severe stomach/abdominal pain, yellowing eyes/skin, chest pain, shortness of breath.

A very serious allergic reaction to this drug is rare.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.


Common side effects:
  • • Constipation or diarrhea
  • • Stomach pain
  • • Nausea
  • • Sinus pain or sore throat
  • • Back pain and headaches
  • • Stuffy nose
  • • Flu-like symptoms
  • • Abnormal liver function
  • • Rashes
  • • Hair Loss


Allergic Reactions:
  • • Hives
  • • Swelling in the oral regions
  • • Breathing problems


Severe Reactions:
  • • Stomach cramps
  • • High fever
  • • Bloody stools
  • • Dark urine
  • • Jaundice
  • • Pain during micturition
  • • Fibrotic lung reaction

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This information does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Certain vitamin supplements, herbs, and drugs, like Mercaptopurine, azathioprine and NSAIDs (nonsteroidal anti-inflammatory drugs), such as ibuprofen, aspirin, etc. react with Mesalamine.

Inform your doctor of your previous medical history before taking any medicine.


  • • Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, stomach blockage (such as pyloric stenosis).
  • • During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
  • • Consult your doctor or pharmacist if you are allergic to it; or to other aminosalicylates (such as balsalazide, olsalazine); or to salicylates (such as aspirin, salsalate); or to sulfasalazine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • • Keep it away from pets and children.
  • • Take the drug as prescribed.
  • • Take regular medical tests to check for any side effects.
  • • Inform your doctors about your medical history.


HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your healthcare professional. Always ask your health care professional for complete information about this product and your specific health needs.


  1. BRAND

    Drug Name

    Prescription Required

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  2. Brand ASACOL 400mg



  3. Brand Asacol MR  400 mg (Product Of UK)



  4. Brand Asacol MR  800 mg (Product Of UK)




    Drug Name

    Prescription Required

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