Retin A Cream (Tretinoin)

Retin A Ointment, a brand-name version of tretinoin, is available by prescription in Ointment form in different strengths. Retin A Ointment is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. You can save on brand name and generic Retin A Ointment by shopping online at our Online Pharmacy.

Retin A Ointment
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Retin A Ointment 0.05%

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Product of India
Manufactured by Johnson & Johnson
As low as $28.62

Retin A Ointment 0.1%

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Product of India
Manufactured by Johnson & Johnson
As low as $16.41

Retin A Ointment 0.4%

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Product of Canada
Manufactured by BAU
As low as $116.67

Retin A Ointment 20gm

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Product of India
Manufactured by Johnson & Johnson
As low as $30.52


What is Retin A Cream used for?

Retin-A cream is a topical application for the treatment of acne vulgaris. RETIN-A (tretinoin) Cream contains tretinoin in either of three strengths by weight of, 0.1%, 0.05%, or 0.025%, in a hydrophilic cream combination of stearic acid, sorbic acid, poly oxyl 40 stearate, stearyl alcohol, isopropyl myristate, butylated hydroxytoluene, xanthan gum, and purified water.
Tretinoin is a medication used to treating acne, fine lines, dark spots, surface wrinkles, and sun-damaged skin. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Tretinoin belongs to a class of medications known as retinoids. It works by affecting the growth of skin cells. Tretinoin is also known as retinoic acid. It’s the generic name for synthetic vitamin A and sold under many different brand names. Retin-A is one of those brand names and can be easily confused with retinol.

How should Retin A Cream be used?

Retin-A cream is applied to the skin, over the affected where acne lesions are most prone to appear, once a day before bedtime for best results. Before applying this medication, wash your hands. Clean the affected skin gently with a mild cleanser and pat it to dry. Squeeze about a half-inch or less of medication onto the fingertip. It should be enough to cover your entire face. Constant use will allow you to understand how much quantity is required for you. On applying the right amount the medication should become invisible almost immediately. If it is still visible, that means you are using too much.
After the application of the cream, you may experience slight warmth or mild stinging transitory feeling. You may temporarily discontinue therapy or reduce the frequency of application as per the requirement with each case. When the patients become able to tolerate the treatment, therapy may be resumed or the frequency of application increased according to your comfort level.
Due to the action of the medication deep in the underlying skin layers, the possibility of an exacerbation of inflammatory response or lesions could occur. This is a normal process and not any sign that the treatment should be discontinued. Any alterations in drug concentration or dose frequency must be carefully monitored through observation of the skin tolerance with the clinical therapeutic topical application.

What if I miss the dose of Retin A Cream?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What are the side effects of Retin A Cream ?

True contact allergy to topical tretinoin is rarely encountered. The individuals with certain sensitive skin may notice excessively red, oedematous, blistered, or crusted appearance over the applied skin area. If these effects are seen, the medication should either be discontinued until the skin integrity is restored or if the medication has been adjusted to a level that the patient can tolerate.
Certain individuals have been known to report sensitivity to sunlight during the course of treatment with Retin-A. However, upon discontinuing the therapy, all adverse effects of Retin-A have been successfully reversible.

Drug Interactions

Topical medication, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and cosmetic products with high concentrations of alcohol, astringents, spices or lime should be used with caution because of possible interaction with tretinoin. Special caution must be exercised when using preparations or products that contain sulfur, resorcinol, or salicylic acid with RETIN-A. It is advised before use of RETIN-A is begun, to “rest” a patient's skin until the effects of such preparations subside.
There are well-controlled studies tested for harmful effects in pregnant women. Tretinoin should be used sparingly during pregnancy only if the potential benefit justifies the potential risk to the fetus.
It is not yet known whether this drug is excreted in breast milk. Because there is evidence of drugs that are excreted in breast milk. Special caution should be exercised when RETIN-A is administered to a nursing woman.


Sunlight exposure, including sunlamps, should be minimized during the course of RETIN-A treatment, and patients with sunburn should be advised not to use the product until fully recovered due to the increased sensitivity to sunlight as a result of the use of tretinoin. Extra caution has to be taken for individuals who may be required to have considerable sunlight exposure due to occupational or other reasons. The use of sunscreen products and protective clothing to cover the treated areas of skin is highly advised in such cases. Medication should be immediately discontinued if a sensitivity reaction or chemical irritation is experienced.

Is Generic available for Retin A Cream?

Yes, Generic equivalent version of Retin A Cream, Tretinoin is avialble in the market.

Can I buy Retin A Cream without prescription?

No, a valid prescription is required for this medication.


  • 2020. Drugs & Medications. [online]
  • Healthline. 2020. Tretinoin Cream: Skin Benefits, How To Use, Side Effects. [online]
  • RxList. 2020. Retin-A (Tretinoin): Uses, Dosage, Side Effects, Interactions, Warning. [online]


HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Author: Dr. Shruthi Shridhar, MD Physician

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Dr. Shruthi Shridhar is an MD Physician and a Clinical Nutritionist with over 9 years of clinical experience. She is an accomplished medical writer and has worked with a variety of specialist physicians like an MD physician, a gynaecologist, a paediatrician, and an orthopaedic and has gained optimal clinical knowledge.

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