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Uloric

Uloric

Also Known as: Uloric, Adenuric, etc.

Active Ingredients: : Febuxostat (feb UX oh stat), available in two dosages of 40 mg and 80 mg

Inactive Ingredients: Hydroxypropyl Cellulose, Sodium Croscarmellose, Microcrystalline Cellulose, Lactose Monohydrate, Magnesium Stearate, Silicon Dioxide, and Opadry II green coating.

Drug Information

Febuxostat, sold under the trade name of Uloric is a non-hygroscopic oral tablet is insoluble in water and freely/sparingly soluble in some of the organic solvents. It functions as a xanthine oxidase inhibitor that melts at temperatures above 200°C.

It was first discovered and used as a drug for clinical trials by drug scientists at Teijin (a Japanese pharmaceutical company) in the year 1998. It is basically used as an analgesic for the treatment of hyperuricemia and chronic gouts.

Why is it prescribed

Increased level of uric acid forms gouts within the body. A gout is a form of arthritis that results from the accumulation of uric acid crystals in the joints. Febuxostat inhibits xanthine oxidase (an enzyme involved in the metabolism of purine bases), which ultimately stops the production of uric acid in the body.

Clinical studies state that Febuxostat is more effective than the standard prescribed dosage of allopurinol (another drug used for lowering high uric acid levels in the blood). It is only recommended to the patients who are intolerant or allergic to allopurinol.

How to use Uloric

Physicians prescribe Febuxostat based on a patient’s weight, health and response to medical treatment. The standard dosage is maintained within the range of 40 mg to 80 mg, starting with 40 mg initially.

Patients are recommended to take Uloric tablets once a day, with or without food. Ideally, it is not a pain killer therefore, doctors prescribe painkillers like colchicine, naproxen, ibuprofen, and NSAIDs along with an antacid, if required.

Take medicine at the same time every day to get the maximum benefit of the treatment. Patients may experience gout attacks for an initial few weeks until the medicine completely removes uric acid from the bloodstream.

What if I Miss a Dose or Overdose?

Take the missed dose as soon as you remember, unless it is colliding with the time for the next dose. Maintain a gap of at least 18 to 20 hours between two subsequent doses.

Uloric overdose symptoms include breathing problems, unconsciousness, and restlessness. If you experience such reactions, make sure to contact 911 or 1-800-222-1222 (National Poison Helpline).

Uloric Side Effects

Allergic Reactions:

  • Swelling in the oral regions
  • Hives
  • Breathing problems
  • A sore throat
  • Fever
  • Inflammation
  • Skin rash
  • Blisters, peeling, dryness
  • Burning sensation in the eyes.

 

Common Side Effects:

  • Joint Pain
  • Gout Flares
  • Muscle aches
  • Weakness
  • Slight bruising
  • Nausea
  • Abnormal stomach aches

 

Serious Symptoms:

  • Heart attack
  • Liver malfunctioning
  • Jaundice
  • Dark urine
  • Stroke
  • Poor balance and vision

You may report the side effects at 1-800-FDA-1088.

Drug Interactions

Being an XO inhibitor, Uloric affects the metabolism of theophylline (an XO substrate). Therefore, drugs metabolized by XO, which includes azathioprine and mercaptopurine are likely to react with it.

Precautions

  • Make sure that you share your medical history with the pharmacist before taking Uloric, especially if you have been treated for stroke, cancer or disorders of liver, kidney, and heart.

  • Check with your doctor if you’re planning to go under the knife.

  • Do not take it when you’re expecting or breastfeeding, unless prescribed by the doctor.

  • Never share your dose with others. Do not tamper with the dose on your own.

  • Keep the medicine away from kids and pets.

Key Facts

  • Uloric has been evaluated for safety in over 4000 patients, for more than five years.

Important

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your healthcare professional. Always ask your health care professional for complete information about this product and your specific health needs.

·          

  1. GENERIC

    Drug Name

    Prescription Required

    Salt Name

    Action

  2. GENERIC EQUIVALENT TO ULORIC 40mg

    Yes

    Febuxostat

  3. GENERIC EQUIVALENT TO ULORIC 80mg

    Yes

    Febuxostat

! Important Note: We do not dispense any prescription medicine without valid and legible prescription written by your local Physician. All prescriptions must be presented from a verifiable and licensed physician.

! Important Note: We are only able to ship a maximum 90-day supply of your prescription.

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