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Also Known as: Januvia (jah-NEW-vee-ah), Januvia tab

Active Ingredients: Sitagliptin (pronounced as sit a glip' tin), which is present as sitagliptin phosphate—an orally-active compound that inhibits DPP-4 (dipeptidyl peptidase-4) enzyme.


A film-coated tablet of Januvia contains sitagliptin phosphate monohydrate in different concentrations—32.13, 64.25, or 128.5 mg.

Inactive Ingredients: Anhydrous Dibasic Calcium Phosphate, Microcrystalline Cellulose, Sodium Stearyl Fumarate, Magnesium Stearate, and Croscarmellose Sodium. The film ingredients include Talc, Polyethylene Glycol, Polyvinyl Alcohol, Yellow Iron Oxide, Red Iron Oxide, and Titanium Dioxide.

Drug Information

Sitagliptin or Januvia was initially identified as MK-0431. The anti-hyperglycemic or anti-diabetic oral drug was sold in the form of a phosphate salt, by Merck & Co. It is used in combination with other oral anti-diabetic drugs, such as Thiazolidinedione and Metformin for treating diabetes mellitus type II.

The drug is prescribed with exercises and diet therapy to treat diabetes symptoms.

Why is Januvia (Sitagliptin ) Prescribed?

Diabetics have a high level of sugar in the blood. Consequently, they develop life-threatening complications like poor vision, stroke, heart diseases, nerve damage, kidney issues, gum disease, impotence, etc.

Sitagliptin triggers the production of natural substances (incretin) that lower blood sugar. Incretin increases the insulin level in the body, after a meal. It also decreases the production of sugar (glucose) in the liver. Januvia doesn’t treat type I Diabetes.

How to use Januvia

Doctors prescribe a standard dose of 100 mg, once a day. You may take it with water, with or without food, as directed by the doctors. Your blood sugar levels may fluctuate after taking the drug. Sometimes, doctors prescribe a lower dose of sulfonylurea (insulin secretagogue) to avoid the risks associated with hypoglycemia.

What if I Miss a Dose or Overdose?

If you miss a dose, take the tablet as soon as you remember, but do not take two doses close together. If you overdose on Januvia, and experience symptoms like breathing issues, unconsciousness, etc. immediately seek medical help at 911 or 1-800-222-1222 (National poison control center).

Januvia Side Effects

Common side effects:
  • • Hypoglycemia or low blood sugar (characterized by symptoms like nausea, hunger, headache, irritability, sweating, dizziness, seizures, etc.)
  • • Hyperglycemia or high blood sugar (the symptoms include frequent urination, thirst, flushing, drowsiness, confusion, fruity breath odor, rapid breathing, etc.)
  • • Allergic reaction (hive, rash, itching, swelling, etc.
Serious side effects:
  • • Pancreatitis (loss of appetite, vomiting, nausea, severe pain in abdomen)
  • • Autoimmune reaction (blisters, itching and skin breakouts)
  • • Joint pain
  • • Kidney problems
  • • Heart problems
  • • Respiratory issues
  • • Shortness of breath
  • • Rapid weight gain
  • • Swelling in the body

Drug Interactions

Januvia may react when taken in combination with certain herbs, dietary supplements, prescription and non-prescription drugs, such as:

  • • Insulin
  • • Lanoxin, Lanoxicaps, etc.
  • • Oral anti-diabetic medicines, such as Glimepiride (Amaryl), Chloropropamide (Diabinese), Glyburide (DiaBeta), Glipizide (Glucotrol), Tolbutamide, Tolazamide (Tolinase), etc.
  • • Beta-blockers like Propranolol, Metoprolol, etc. may produce violent reactions during hypoglycemia (when blood sugars dip low).

Inform your doctor of your previous medical history before taking any medicine.


  • • Make sure you inform your pharmacist about your previous medical history and allergies, especially if you’ve experience kidney diseases, heart diseases, gallstones, or pancreatitis in past.
  • • Avoid taking the medicine when your body is under stress due to injury, infection, fever, etc.
  • • Inform your doctor if you are planning a pregnancy, dental procedure, or surgery.
  • • Do not drive, operate a machinery or perform intense physical activity after taking the medicine, as it may cause dizziness, blurred vision, and drowsiness.
  • • Keep the medicines away from children and pets.
  • • Always keep a source of fast-acting sugar with you (like raisins, non-diet soda, candy, and fruit juice) should your blood sugar dip low.


HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your healthcare professional. Always ask your health care professional for complete information about this product and your specific health needs.


  1. BRAND

    Drug Name

    Prescription Required

    Salt Name


  2. Brand Januvia 25mg



  3. Brand JANUVIA 50mg



  4. Brand JANUVIA 100mg



! Important Note: We do not dispense any prescription medicine without valid and legible prescription written by your local Physician. All prescriptions must be presented from a verifiable and licensed physician.

! Important Note: We are only able to ship a maximum 90-day supply of your prescription.

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